@jauhar123 | Posted 31 Jul. 2019
Pharmaceutical formulation is the process of mixing various chemical substances with the active drug to get the desired final medicinal product, which is called a drug mixture or a drug formulation.
A drug formulation is given to the patient in various forms like solid, semi-solid, or liquid. The type of the formulation, provided by the Formulation Development Services, the patient receives upon the patient’s age, *****, and health condition and differs for particular routes of administration.
Tablets: A tablet is disc-shaped and is prepared by compressing a granulated powder in a dye of suitable machinery. They are usually coated with inert substances such as starch to help them break and spread in the digestive tract of the patient. A lubricating material, binding agent, and flavors are included in the tablets to make them palatable. Enteric Coated Tablets: These tablets are coated with a material that does not disintegrate in the acidic medium of the stomach but dissolves in the alkaline medium of the intestine. They can’t be chewed but can be consumed only by swallowing.
Controlled Release Tablet: These tablets are designed to release the active ingredient of the drug in a certain amount over a specified period. Here, the quantity of drug released is gradual over the day and does not rely upon the pH of the digestive tract of the patient. Therefore, a uniform amount of drug is released at a steady rate.
Sustained Release Preparations: They release a fixed amount of drug over a long period. Hence, they improve treatment compliance by the patient.
Capsules: They can be hard or soft. Hard capsules have the drug in solid form, which easily gets dissolved in water. Soft capsules contain the drug in liquid or semi-solid form, which is insoluble in water and soluble in glycol or propylene.